25 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... Skin involvement, Kidney ... injury, Previous ... #Algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... or symptoms of liver ... Drug #induced #Liver ... gastroenterology #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • Iatrogenic: DILI ... extrahepatic source - Tests ... differential #diagnosis #algorithm
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... skeletal muscle, kidneys ... bilirubin (Conjugated/DBili ... hepatocellular injury ... #Function #Tests
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... skeletal muscle, kidney ... abnormality vs bone Bili ... Hepatocellular injury ... 2: Cholestatic injury
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Tests (LFTs) - ... (>1000): • DILI ... injury) • Ischemic ... #Function #Tests
# Acute Kidney Injury # AKI #algorithm #differential #nephrology
# Acute Kidney Injury ... # AKI #algorithm ... #differential #nephrology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... disease, liver ... support, or liver ... Circulation Failure Kidney ... Injury (DILI)
Differential Diagnosis of Acute Kidney Injury 

#Diagnosis #Nephrology #AKI #Acute #KidneyInjury #Causes #Differential #Workup #Algorithm #Ddxof
Diagnosis of Acute Kidney ... Injury #Diagnosis ... #Nephrology #AKI ... Differential #Workup #Algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
cardiac muscle, RBC, Kidney ... Cardiac muscle, Kidneys ... trimester placenta, kidneys ... Unconjugated Bili ... > 90% of Total Bili