9 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... HSV • Toxic: Alcohol ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... test abnormalities ... Drugs (MDMA), Alcohol ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... extrahepatic source - Tests ... ALT Ratios: • Alcoholic ... #injury #hepatitis ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Circulation Failure Kidney ... Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... Injury (DILI) ... Failure #Cirrhosis #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... Skin involvement, Kidney ... HEV, EBV, CMV), Alcohol-related ... • Autoimmune hepatitis ... #Algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... ALT Ratios: • Alcoholic ... Cardiac muscle, Kidneys ... #differential #Hepatology
Autoimmune Hepatitis - Testing Algorithm
Individual Tests:
 • F-Actin (Smooth Muscle) Antibody, IgG by ELISA with Reflex
Autoimmune Hepatitis ... Individual Tests ... IgG by IFA • Liver ... /Kidney Microsome ... #hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... Treatment: - Acute kidney ... injury with serum ... #Algorithm #hepatology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
cirrhosis, severe alcoholic ... hepatitis, or acute ... insult (e.g., alcohol ... Hepatorenal #Syndrome #Hepatology ... #Nephrology #Diagnosis