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diagnosis differential rheumatology neurology clinical dermatology management vasculitis comparison endocrinology erythematosus hematology infectiousdiseases lupus oncology primary pulmonary secondary sle workup
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... elbows/wrists and knees ... skin thickening Signs ... (interstitial lung ... rheumatology #diagnosis #signs
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Adrenals: • Lung ... vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... endocrinology #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Problem Representation - Approach to the Infectious Disease Patient Who: Patient age and host/risk factors (such as
Approach to the Infectious ... Disease Patient ... illness What: Key signs ... and symptoms that ... e.g. brain and lung
Bilateral B-Lines in case of Pneumonia on Lung POCUS Young healthy pt with fever/dyspnea. POCUS lung exam
POCUS lung exam ... disease, interstitial ... diffuse infections ... Lung POCUS shows ... partially seen shred sign
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 Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... Other auto-immune, Infectious ... autoantibodies #signs ... #symptoms #mimickers
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... (AQP4-lgG disease ... autoimmune disorders (Systemic ... diagnosis #neurology #symptoms ... #signs
Causes of Peripheral and Central Vertigo PERIPHERAL VERTIGO 1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
history of viral infection ... Long symptom-free ... (Wallenberg's syndrome ... Syndrome usually ... varying neurologic signs
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... • Mounier-Kuhn syndrome ... Nasal polyps and signs ... in the adjacent lung ... of the affected lung
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Causes: • Still's ... • Behcet's syndrome ... • Hyper-IgD syndrome ... Brucellosis Faget's Sign ... Brucellosis • Liver or lung
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