24 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... elbows/wrists and knees ... skin thickening Signs ... (interstitial lung ... rheumatology #diagnosis #signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
effusion, Restrictive lung ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... (AQP4-lgG disease ... autoimmune disorders (Systemic ... diagnosis #neurology #symptoms ... #signs
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... Less Specific Signs ... Chest x-ray: signs ... acute HF → no signs ... coronary artery disease
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Causes of Peripheral ... Long symptom-free ... (Wallenberg's syndrome ... Syndrome usually ... varying neurologic signs
Rare Causes of Abdominal Pain
 • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
- May involve symptoms ... cardiovascular system ... neuropsychiatric symptoms ... patient is in the knee-to-chest ... Positive Carnett's sign
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... granulomas within the lungs ... the lymphatic system ... 5-10%, nervous system ... #Signs #Symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... Systemic disease ... meningitis), MCC CNS symptoms ... #diagnosis #management ... #signs #symptoms
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Episcleritis Signs ... and Symptoms: ... development of skin symptoms ... Causes: - Idiopathic