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management diagnosis antiphospholipid aps guidelines hematology sle druginduced erythematosus eular2019 systemic table activation anticoagulation associations autoantibodies cerebritis cns comparison dil
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Puncture, EEG Treatment ... (for secondary APS ... CNS #neurology #rheumatology ... diagnosis #management #treatment
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Anti-cardiolipin (aCl ... glycoprotein I (ß2GP), Lupus ... LAC) • Sjogren Syndrome
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... (APS) APS is a ... antibodies (aPL): • Lupus ... to be present Treatment ... Antiphospholipid #Syndrome
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... have fever - ACS ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS Venous Thrombosis - Arterial Thrombosis INR Target Duration Recurrence Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... Antiphospholipid #Syndrome ... #APS #management ... EULAR2019 #guidelines #rheumatology ... #hematology #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... thiazidic, PPI, ACE ... constitutional symptoms • Treatment ... life-threatening • Treatment ... comparison #table #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as ... disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Rheumatology
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS Previous Thrombosis? Previous Pregnancy Complications? Dr. Laurent ARNAUD @Lupusreference #obstetrics
Antiphospholipid Syndrome ... ) APS Previous ... Antiphospholipid #Syndrome ... EULAR2019 #guidelines #rheumatology ... #obgyn #treatment
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... thiazidic, PPI, ACE ... constitutional symptoms • Treatment ... #DIL #rheumatology ... #diagnosis #treatment
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