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diagnosis differential algorithm hypernatremia management causes insipidus 1 2 3 alkalosis chloride defects di epithelial high inherited kidney metabolic polydipsia
Causes of Hypernatremia - Differential Diagnosis Inadequate water intake: • Lack of access to water Extrarenal hypotonic fluid
diuresis • Central diabetes ... • Nephrogenic diabetes ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup Step #1 - Consider the history Step #2 - Assess
Diagnosis Algorithm - Diabetes ... Management #Algorithm #Sodium ... #nephrology #insipidus
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
water loss, Serum Sodium ... 300 mmol/kg • Diabetes ... Hypernatremia #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
cell epithelial sodium ... of epithelial sodium ... ATPase Nephrogenic diabetes ... Defects #Kidney #Nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
• Euvolemic: Diabetes ... Workup #Algorithm #nephrology ... #sodium
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
metabolic acidosis • Diabetic ... settings, the urine sodium ... the excretion of sodium ... urine #Algorithm #nephrology
Hypernatremia - Differential Diagnosis and Treatment Hypernatremia is almost always due to unreplaced water loss (free water
post-obstructive 3) Diabetes ... Treatment #management #nephrology ... #sodium
Diabetes Insipidus - Diagnosis Algorithm Tests: • Osmolality, Urine AND/OR • Osmolality, Serum or Plasma AND •
Diabetes Insipidus ... Plasma AND • Sodium ... ARUPConsult @ARUPLabs #Diabetes ... Diagnosis #Algorithm #nephrology
Primary Polydipsia Definition: Excessive volitional water intake Epidemiology: • 6-20% of patients with psychiatric disorders - Most commonly
- Co-morbid diabetes ... Differential Diagnosis: Diabetes ... Urine Osm, Serum Sodium ... , Urine Sodium ... diagnosis #management #nephrology
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