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diagnosis hepatology transaminitis algorithm causes hepatitis acidosis ascites chemistry classification elevation function gap globulin hematology hepatitisb hepatocellular hepbv indications interpretation
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... • NAFLD • Cirrhosis ... Hepatopathy • Acute ... injury) • Ischemic
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Liver Injury: ... , HBV, HCV, HEV, ... hepatitis: < 1 • Cirrhosis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Family history of cirrhosis ... or fibrosis • Cirrhosis ... severe liver injury ... > 3 mg/dL) or acute ... liver failure
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... #LFTs #transaminitis ... #differential #
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... #Injury #Differential ... Transaminitis #LFTs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... hepatitis serologies, HCV ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential ... transaminitis #LFTs
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... C, A, E, B, D, EBV ... , CMV, HSV • Toxic ... #Injury #Differential
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... - Cirrhosis ... fibrosis - Acute ... fatty liver of ... Causes #diagnosis #differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... or renal injury ... cardiac output - Acute ... peritonitis - Acute ... Injury: • Reduced
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Viral infections (acute ... Sarcoidosis) • Liver ... disease: Cirrhosis ... inflammation (acute ... Gap #ProteinGap #differential
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