100 results
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
IGG-4 RELATED DISEASE ... infiltration of IgG4 ... lesions - IgG4 ... Biliary Tract: IgG4 ... Küttner tumor (Submandibular
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... parotid gland, submandibular ... node), high serum IgG4 ... with increased IgG4 ... Mettler_K1000 #IgG4
Submandibular Neck Triangle Anatomy

By @rev.med

#Submandibular #Neck #Triangle #Anatomy #Otolaryngology
Submandibular Neck ... By @rev.med #Submandibular
Salivary Gland Anatomy
 - Parotid Glands
 - Sublingual Glands
 - Submandibular Glands

By @rev.med

#Salivary #Glands #Anatomy #Salivation
Sublingual Glands - Submandibular
Cervical Lymphadenopathy - Lymph Node Drainage
Preauricular nodes - Drain scalp, skin
 • Differential diagnosis: Scalp infections,
Abdominal/thoracic Submandibular ... diagnosis: Same as submandibular
IgG4-associated conditions

Diagnosis of IgG4 disease is depending on BIOPSY. While IgG4 levels can be informative (and
IgG4-associated ... Diagnosis of IgG4 ... While IgG4 levels ... inflammation of IgG4 ... #IgG4 #conditions
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
Manifestations of IgG4 ... #IgG4 #Manifestations
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
AIHA: - 70%; IgG ... mediated - DAT: IgG ... mediated - DAT: IgG
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
DAT Poly ( - ), IgG ... DAT Poly ( + ), IgG ... DAT Poly ( + ), IgG ... Poly ( +/- ), IgG ... DAT Poly ( + ), IgG
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
rheumatoid arthritis, IgG4