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Immune-related adverse events (irAE) of  immune checkpoint inhibitors (ICI) 

- By Antoine Briantais 
Dr. Benjamin
Immune-related adverse ... events (irAE) of immune ... checkpoint inhibitors
Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
 -
Side Effects - Immune-related ... - Immune-related ... - Most immune-related ... by stopping the checkpoint
Immune Checkpoint Inhibitors

PD-1 inhibitors
 - Nivolumab
 - Pembrolizumab
CTLA-4 inhibitors
 - Ipilimumab
 - Tremelimumab
PD-L1 inhibitors
 - Atezolizumab
Immune Checkpoint ... Durvalumab #Immune ... #Checkpoint #Inhibitors
Checkpoint Inhibitors: Immune-Related Adverse Events (irAEs)

#Checkpoint #Inhibitors #SideEffects #AdverseEffects #irAEs #diagnosis #Incidence
Checkpoint Inhibitors ... : Immune-Related ... Events (irAEs) #Checkpoint
The Cell Cycle
The cell cycle is the series of tightly regulated steps that controls cell growth
through the G1/S checkpoint ... /S, S/G2, G2/M checkpoints ... the cell cycle checkpoints ... Ever had bad sunburn ... proliferation #TF #E2F #checkpoint
Myocarditis 

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic
anti-metabolite - Immune ... Checkpoint Inhibitors
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Bowman's space) Immune-Complex ... • Presence of immune ... deposits Pauci-lmmune ... • Minimal immune
Immune Checkpoint–Blocking Antibodies Approved by the Food and Drug Administration #Pharm #Honc #Checkpoint #Blockade #FDA #Antibodies
Immune Checkpoint–Blocking ... #Pharm #Honc #Checkpoint
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Erdheim-Chester), Immune ... Checkpoint Inhibitors
Management of Immune Thrombocytopenia (ITP) . 

#Idiopathic #Thrombocytopenic #Purpura #Immune #Thrombocytopenia #ITP #Management #Hematology
Management of Immune ... Thrombocytopenic #Purpura #Immune