13 results
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
Endocarditis (IE ... therapy - Number one cause ... of culture negative ... #Diagnosis #Management ... #Algorithm
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
), Spontaneous rupture ... infarction, Tendineae rupture ... Papillary muscle rupture ... Regurgitation #differential ... #diagnosis #cardiology
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... infective endocarditis ... identified with modern culture ... #differential # ... #culture #negative
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
Endocarditis Algorithm ... Noninfective Causes ... • HACEK • Culture-negative ... #Algorithm #Infective ... #Differential #
Systolic Murmurs - Differential Diagnosis Algorithm
Benign / Flow / Hyperdynamic:
 • Pregnancy
 • Fever
 • Anemia
Supravalvular
Diagnosis Algorithm ... Chordae Tendinae • Rupture ... • Infarct • Rupture ... Systolic #Murmurs #Cardiology ... #causes
Blood Culture Collection Algorithm - Adult Patients with Suspected Systemic Infection 

Pawlowicz et al evidenced based
Blood Culture Collection ... Implementation-of-an-evidence-based-algorithm-reduces-blood-culture-overuse-in-an-adult-emergency-department.php ... have unstable vital ... , endocarditis, ... #Management #BloodCultures
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... identified with modern culture ... - Standard culture ... #Infective #Endocarditis
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... Culture (+): ... • Coagulase-negative ... staphylococci Culture ... #cardiology
Causes of Primary and Functional Mitral Regurgitation (MR) 
Causes of primary mitral regurgitation
 - Rheumatic heart
stenosis - Infective ... /marantic endocarditis ... MV chordae may rupture ... laterally from myocardial ... #Diagnosis #Cardiology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
involves aortic and mitral ... Culture Positive ... staphylococci Culture ... • Persistent bacteremia ... Diagnosis #cardiology