11 results
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... nutritionally variant Strep ... identified with modern culture ... #differential # ... #culture #negative
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
), Spontaneous rupture ... infarction, Tendineae rupture ... Papillary muscle rupture ... #differential # ... diagnosis #cardiology
Systolic Murmurs - Differential Diagnosis Algorithm
Benign / Flow / Hyperdynamic:
 • Pregnancy
 • Fever
 • Anemia
Supravalvular
Systolic Murmurs - Differential ... Chordae Tendinae • Rupture ... • Infarct • Rupture ... Systolic #Murmurs #Cardiology ... Diagnosis #Algorithm #causes
Approach to the Hypotensive Patient - Differential Diagnosis Framework for Hypotension

Blood Pressure = Heart Rate x
dysfunction - Myocardial ... - Free wall rupture ... Papillary muscle rupture ... stenosis • Meds: negative ... #diagnosis #causes
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Culture (+): ... • Coagulase-negative ... staphylococci Culture ... #diagnosis #management ... #cardiology
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Causes of Severe ... - Differential ... Leaflet: Traumatic Rupture ... #Differential # ... #cardiology
Streptocccus Pneumoniae
Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative
Epidemiology - 10% adult carriers:
 • Most common cause of:
Alpha-hemolytic, Catalase Negative ... • Most common cause ... sinus • Sputum culture ... Streptocccus #Pneumoniae #strep ... microbiology #diagnosis #management
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... but important causes ... nutritionally variant Strep ... identified with modern culture ... - Standard culture
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential ... Culture Positive ... staphylococci Culture ... #Differential # ... Diagnosis #cardiology
Causes of Primary and Functional Mitral Regurgitation (MR) 
Causes of primary mitral regurgitation
 - Rheumatic heart
Infective/marantic endocarditis ... MV chordae may rupture ... laterally from myocardial ... #Functional #Differential ... #Diagnosis #Cardiology