10 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
and Vasoactive Drugs ... pharmacology ... #pharmacology # ... inopressors #diagnosis ... #management #comparison
Carbamazepine Toxicity

Carbamazepine (CBZ) is an antiepileptic drug commonly prescribed for seizure disorders, trigeminal neuralgia, neuropathic pain,
Carbamazepine Toxicity ... antiepileptic drug ... Carbamazepine #Toxicity ... #Toxicology #Diagnosis ... SideEffects #Adverse #Pharmacology
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
Antipsychotic Drugs ... Antiparkinsonian agents are diagnostic ... dose or change drug ... facies, shuffling gait ... #SideEffects #pharmacology
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
Therapeutic Drug ... at anytime if toxicity ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
antipsychotic drugs ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
brain • Weight Gain ... irreversible • Drug ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Drug-Induced Prolonged ... Pointes (TdP) Drugs ... Prolonged #QTc #Toxicity ... #Toxicology #Pharmacology ... #Diagnosis #prolongation
Lithium Therapy for Bipolar Disorder 
Toxicity Levels: 
 - Mild (1-1.5 mEq/L) 
 - Moderate (1.6-2.5
Bipolar Disorder Toxicity ... polyuria, weight gain ... Common drug interactions ... include these drugs ... #Pharmacology #
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
A dissociative drug ... glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic ... #CriticalCare #diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
superinfection, drug ... blindness, or gait ... : • Drug reaction ... /ART toxicity ... active infection/drug