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antinuclear autoantibodies classification differential cryoglobulinemia cryoglobulins sle systemic types vasculitides
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... cases • Sjögren syndrome ... #ANCA #Antineutrophil ... #antibodies #diagnosis ... #rheumatology #
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Syndrome: Anti-cardiolipin ... LAC) • Sjogren Syndrome ... Ill • ANCA Vasculitis ... #diagnosis #associations
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... La) - Sjogren's syndrome ... c-ANCA - Vasculitis ... #diseases #diagnosis ... #table #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... : The ANA patterns ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ACLE) • Erythematous ... rheumatologic diseases ... lymphoma • Evans' syndrome ... Shrinking lung syndrome ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... ) pattern: antibodies ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... Cryoglobulinemia Syndrome ... 20% Sjögren's syndrome ... DDX: • ANCA (Antineutrophil ... classification #rheumatology
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