1651 results
Insulin and Glucagon Pathophysiology
Insulin: 
 • Glucose utilization (Glycolysis)
 • Glucose storage (Glycogenesis)
 • Fat synthesis
Insulin and Glucagon Pathophysiology ... Glycogenesis) • Fat synthesis ... tissues Glucagon Actions ... : • Glucose synthesis ... Insulin #Glucagon #Pathophysiology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Prostaglandin Synthesis ... prostaglandin synthesis ... , leaving actions ... #Pharmacology #Pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... Hepatic Bile Acid Synthesis ... sequestration #pathophysiology
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
Sources: dermal synthesis ... products, fish) Active ... endocrinology #pathophysiology
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
: Mechanism of Action ... anti-fibrinolytic - TXA is a synthetic ... Tranexamic #Acid #pathophysiology
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen Pathophysiology ... macrophages) → Synthesis ... vasculature via: • Active ... Pyrogen → Induce synthesis ... Fever #Fever #Pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Vit-D (1-25-OH2) synthesis ... and action -> Decr ... #Osteoporosis #pathophysiology
Calcium homeostasis is a process controlled by chiefly by hormones vitamin D and PTH. 
Vitamin D
circulation via synthesis ... converted to its active ... by increasing active ... #Pathophysiology
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... Macrophages → Synthesis ... vasculature via: • Active ... pyrogen induces synthesis ... Rigors #Bacteremia #Pathophysiology
Drugs with Actions on Bronchial Smooth Muscle
Bronchodilation is promoted by cAMP. Intracellular levels of cAMP can
Drugs with Actions ... the rate of its synthesis ... #SmoothMuscle #Pathophysiology