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Thyroid Function Pathway 

Hypothyroidism is a very common condition! Here's a repost of the pathway that
stimulate more T4/T3 ... Thyroid #Pathway #Pathophysiology
Thyrotoxic Periodic Paralysis - Illness Script
 • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
and menses • Pathophysiology ... high fT4 or high T3
Thyroid Function Tests (TFTs) and Interpretation

 • TSH, Free T4, Free T3
 • T3 Uptake
 •
Free T4, Free T3 ... • T3 Uptake ... FTI) • Reverse T3
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
in some cases, T3 ... low; free T4 and T3 ... low; free T4 and T3 ... low; free T4 and T3 ... low; free T4 and T3
Approach to the Diagnosis of Hyperthyroidism - Differential Diagnosis and Workup Algorithm

 • Secondary Hyperthyroidism (↑↔TSH,
↑↔TSH, ↑Total T3 ... (↓TSH, ↔Total T3 ... (↓TSH, ↑Total T3 ... (↔TSH, ↔Total T3
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
normal T4 +/- T3 ... TSH, high T4 +/- T3 ... TSH, high T4 +/- T3
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
conversion of T4 to T3 ... conversion of T4 to T3 ... conversion ofT4 to T3
Thyroid Function Test Interpretation Table

TSH, Free T4, Free T3 and Associated Condition
#Diagnosis #Endocrinology #Hyperthyroid #Hypothyroid #Function
Free T4, Free T3
Algorithm for the diagnostic workup of hyperthyroidism. (T3 = triiodothyronine; T4 = thyroxine; TSH = thyroid-stimulating
(T3 = triiodothyronine
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
thyrotoxicosis • T3 ... TSH • ↑ Total T3 ... ↑ FT4 and/or ↑ T3 ... : Reduce T4 -> T3