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Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
with circulating thyroid ... T3 • ↑ Free T4 ... suspected • Thyroid ... Glucocorticoids: Reduce T4 ... hyperthyroidism #causes
Subacute Thyroiditis Also known as: de Quervain’s thyroiditis, granulomatous thyroiditis, or viral thyroiditis What? Postviral inflammatory process caused by
inflammatory process caused ... in viruses and thyroid ... after onset Causes ... Thyrotoxic phase: ↑ T4 ... Hypothyroid phase: ↓ T4
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
of Patients for Thyroid ... high; in some cases ... iodine uptake; thyroid ... iodine uptake; thyroid ... procedure that ablates thyroid
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... TSH, Low normal T4 ... Low TSH, normal T4 ... Low TSH, high T4 ... symmetrically enlarged thyroid
Thyroid Function Pathway Hypothyroidism is a very common condition! Here's a repost of the pathway that
Thyroid Function ... TSH and a low T4 ... is because if T4 ... stimulate more T4 ... /ambcarerx #Thyroid
Thyroid Function Tests (TFTs) and Interpretation • TSH, Free T4, Free T3 • T3 Uptake •
Thyroid Function ... • TSH, Free T4 ... @DharSaty #Thyroid
Algorithm for the diagnostic workup of hyperthyroidism. (T3 = triiodothyronine; T4 = thyroxine; TSH = thyroid-stimulating
triiodothyronine; T4 ... thyroxine; TSH = thyroid-stimulating
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 Thyroid Function Test Interpretation Table TSH, Free T4, Free T3 and Associated Condition #Diagnosis #Endocrinology #Hyperthyroid #Hypothyroid #Function
Thyroid Function ... Table TSH, Free T4
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm Beta-Blockers • Decreases sympathetic hyperactivity • Partially blocks peripheral conversion
Hyperthyroidism / Thyroid ... conversion of T4 ... Blocks synthesis of thyroid ... conversion of T4 ... release of stored thyroid
Amiodarone Thyroid Complications Amiodarone: - iodine-rich, similar structure to T4, with half life up to 100d
Amiodarone Thyroid ... similar structure to T4 ... - can prevent T4 ... directly toxic to thyroid ... pts w/ latent thyroid
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