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diagnosis kidney renal akd biomarkers definitions differential framework hyperkalemia hyperphosphatemia k laboratory management nsaids pharmacology phosphate potassium prostaglandins treatment workup
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
): • GFR < 60 ... • GFR < 60 ml/min ... • Decrease in GFR ... ): • GFR ≥ 60 ... #nephrology #acute
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
Creatinine: • AKI ... , CKD • Medications ... nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR ... diagnosis #laboratory #nephrology
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR ... Kidney #renal #nephrology
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
t-PA, heparin Acute ... Kidney Disease: • AKI ... , CKD Increased ... Hypoparathyroidism, Acromegaly, FGFR ... Workup #phosphate #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
esp w oliguria / GFR ... Labs: BMP (Assess GFR ... status to improve GFR ... sufficient if intact GFR ... Treatment #potassium #nephrology
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