15 results
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... Using the GFR clock ... #Diagnosis #Nephro ... #CKD #EGFR #Staging
Definitions of AKI, CKD, AKD
Acute Kidney Injury (AKI):
 • Increase in SCr by 2 50% within
): • GFR < 60 ... • GFR < 60 ml/min ... • Decrease in GFR ... ): • GFR ≥ 60 ... /AKD/CKD • No
Complications of CKD
 - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
CKD - Patients ... with stages 1-3 ([GFR ... >30 mL/min) of CKD ... clinically in CKD ... stages 4-5 (GFR
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
Creatinine: • AKI ... , CKD • Medications ... nephroprotective ↓ in GFR ... , CKD • Obesity ... hyperthyroidism ↓ eGFR
Regulation of GFR
Physiologically, GFR is auto-regulated very precisely with changes in the mean arterial pressure (MAP)
Regulation of GFR ... Physiologically, GFR ... tubuloglomerular, and ... the neuro-hormonal ... Pathophysiology #Nephrology #GFR
Adjusted Pain Medication Dosing based on GFR

#Renal #Dosing #Pain #Pharmacology #Opiates #CKD #Gabapentin #Table
Dosing based on GFR ... Pharmacology #Opiates #CKD
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
is increased in CKD ... maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
Renal #Impairment #CKD ... #Table #GFR #Hypoglycemics
Effects of a Low-Protein, Low-Salt Diet on the Afferent Arteriole. A lower intake of dietary protein
glomerular damage and ... #Pathophys #Nephro ... #CKD #LowProteinDiet ... #GFR #NEJM
Effect of Tolvaptan on the Estimated Glomerular Filtration Rate (GFR). #EBM #Nephro #Pharm #Tolvaptam #PCKD #PolyCysticKidneyDisease
Filtration Rate (GFR ... #EBM #Nephro #Pharm ... #Tolvaptam #PCKD