11 results
Definitions of AKI, CKD, AKD
Acute Kidney Injury (AKI):
 • Increase in SCr by 2 50% within
, CKD, AKD Acute ... ): • GFR < 60 ... • GFR < 60 ml/min ... • Decrease in GFR ... ): • GFR ≥ 60
Adjusted Pain Medication Dosing based on GFR

#Renal #Dosing #Pain #Pharmacology #Opiates #CKD #Gabapentin #Table
Dosing based on GFR ... #Dosing #Pain #Pharmacology ... #Opiates #CKD # ... Gabapentin #Table
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
is increased in CKD ... maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
#Medications #Pharmacology ... Renal #Impairment #CKD ... #Table #GFR #Hypoglycemics
Effects of a Low-Protein, Low-Salt Diet on the Afferent Arteriole. A lower intake of dietary protein
Effects of a Low-Protein ... glomerular damage and ... #Pathophys #Nephro ... #CKD #LowProteinDiet ... #GFR #NEJM
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline Causes AKI ... signal to reduce GFR ... - Decreased GFR ... NS #comparison #pharmacology ... #effects
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
channel blocking effects ... Intermediate Action, ↑ EFR ... Fast Action, ↓ EFR ... Slow Action, ←→ EFR ... Vaughan #Williams #Pharmacology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
Empagliflozin and ... Contraindications: eGFR ... ) Common Side Effects ... and Toxicities: ... • AKI (likely
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis and ... esp w oliguria / GFR ... Labs: BMP (Assess GFR ... status to improve GFR ... sufficient if intact GFR
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
channel blocking effects ... and AP duration ... Intermediate Action, ↑ EFR ... Fast Action, ↓ EFR ... Slow Action, ←→ EFR