11 results
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
agents #Diabetes ... #Diabetic #Medications ... #Pharmacology # ... Renal #Impairment #CKD ... #Table #GFR #Hypoglycemics
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... cells, triggering insulin ... contraindicated in CKD ... : Weight gain, Hypoglycemia ... #Summary #DM2 #diabetes
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
Oral Hypoglycemics ... in Diabetes Management ... 1 INSULIN SENSITIZER ... AmyChung #Oral #Hypoglycemics ... #pharmacology #
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
(stage IV or V CKD ... including most type 1 diabetics ... including most 2 diabetics ... Weight #Based #pharmacology ... endocrinology #diabetes
Insulin Dosing Basics - Initiating Insulin for T2DM and Converting Insulin Products 

Insulin dosing can be
Insulin Dosing Basics ... For type 2 diabetes ... for type 2 diabetes ... experience unexplained hypoglycemia ... #Prescribing #Pharmacology
Insulin Degludec (Tresiba) vs Insulin Glargine (Lantus, Basaglar, or Toujeo)

Insulin degludec (Tresiba) is an ultra-long acting
Insulin Degludec ... (Tresiba) vs Insulin ... incidence of severe hypoglycemia ... Glargine #Comparison #Pharmacology ... #DEVOTE #Diabetes
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Management of Diabetes ... Patients With CKD ... evidence-based pharmacologic ... #Diabetes #CKD # ... #KDIGO #eGFR #Insulin
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... • Increases insulin-mediated ... Does not cause hypoglycemia ... #Metformin #Pharmacology ... #Summary #DM2 #diabetes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
transfusions), ↓insulin ... VBG (acidosis), CK ... Treatments: • Insulin ... Give D50 before insulin ... Monitor hypoglycemia
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
-> Stimulates Insulin ... will stimulate insulin ... minimal chance of hypoglycemia ... Renal #Dosing #Pharmacology ... #Management #Diabetes