9 results
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
hypoglycaemic agents #Diabetes ... #Diabetic #Medications ... #Pharmacology # ... Renal #Impairment #CKD ... #Table #GFR #Hypoglycemics
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
(stage IV or V CKD ... including most type 1 diabetics ... including most 2 diabetics ... Weight #Based #pharmacology ... endocrinology #diabetes
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Patients With CKD ... creatinine, & serum K+ ... evidence-based pharmacologic ... #Diabetes #CKD # ... #KDIGO #eGFR #Insulin
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... cells, triggering insulin ... contraindicated in CKD ... Sulfonylureas #Pharmacology ... #Summary #DM2 #diabetes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
transfusions), ↓insulin ... VBG (acidosis), CK ... Treatments: • Insulin ... Give D50 before insulin ... - IV loop diuretic
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
retention of Na, K ... is increased in CKD ... prolonged NSAID use in CKD ... with GFR > 30 and ... renal #nephrology #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia: • CKD ... • Digoxin • K ... (Uncontrolled diabetes ... paralysis - Insulin ... K supplement 3
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia: • CKD ... • Digoxin • K ... (Uncontrolled diabetes ... paralysis - Insulin ... K supplement 3
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
needed, based on K ... patients with CKD ... , HF, or diabetes ... #Hyperkalemia #Pharmacology