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nephrology potassium diagnosis causes differential high management treatment binders binding comparison diuretics drugs excretion hypercalcemia renal
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... , K-sparing diuretics ... VBG (acidosis), CK ... Elimination (see Table ... caution in HTN & edema
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Inhibitors of Na+K+ ... Hyponatremia • Hypercalcemia ... Epithelial Channels (K+ ... #Nephrology #Pharmacology ... #Medications #Table
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... desired serum K ... Side Effects: Edema ... #medications #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... : • CKD • Poorly ... transfusion • HTN and edema ... sparing diuretics ... Medications 2.
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... : • CKD • Poorly ... transfusion • HTN and edema ... sparing diuretics ... Medications 2.
Pharmacologic Options for Hypercalcemia Associated with Cancer Rehydration with NS followed by loop diuretics • IV normal
Pharmacologic Options ... for Hypercalcemia ... followed by loop diuretics ... saline - Enhances GFR ... #table
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