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diagnosis symptoms signs management cardiology differential nephrology pharmacology endocrinology syndrome algorithm causes pulmonary infectiousdiseases msk clinical complications lifecycle ophthalmology hematology
Regulation of GFR Physiologically, GFR is auto-regulated very precisely with changes in the mean arterial pressure (MAP)
Regulation of GFR ... Physiologically, GFR ... Neuro-hormonal feedback #Pathophysiology ... #Nephrology #GFR
Complications of CKD - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
with stages 1-3 ([GFR ... CKD stages 4-5 (GFR ... #Pathophysiology
Fatality / Mortality Calculations in an Outbreak There are a number of different types of rates, risks,
fatality rate (CFR ... Infection-fatality risk (IFR ... fatality risk (HFR
CML Treatment Free Remission (TFR) • Goals of Therapy in CML • CML Rx Milestones
Free Remission (TFR ... ZhuoerXie #CML #TFR
Diabetes Pathophysiology and Medication Targets The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology
Restrictive Cardiomyopathy - Diagnosis and Causes Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema) Physical
Rales,+S4, MR and TR ... Amyloid, Wild Type TTR ... , Senile TTR),
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
T-cells (usually TCR-AB ... phenotype) - Mostly TCR-AB ... for EBER, ALK, TFH ... cells (sCD3-, no TCR
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
Disease (CKD): • GFR ... • AKI, OR • GFR ... • Decrease in GFR ... Disease (NKD): • GFR
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Intermediate Action, ↑ EFR ... Fast Action, ↓ EFR ... Slow Action, ←→ EFR ... Classification #Classes #pathophysiology
Case Fatality Rate (CFR) and R0 of the Novel Coronavirus 2019 compared to other famous contagious
Fatality Rate (CFR ... NCOV2019 #Wuhan #CFR
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