9 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... #Immunology #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Oxyhemoglobin Dissociation ... Oxyhemoglobin #Dissociation ... #Curve #Pathophysiology ... #Differential #Causes
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Fracture • Hip dislocation ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Clindamycin in case ... of PCN allergy ... #differential #causes
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... shifts the oxygen dissociation ... Phosphate is a cause ... the hemoglobin dissociation ... respiratory #hypoxia #pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Albuminocytologic dissociation
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... albuminocytologic dissociation ... the underlying pathophysiology