193 results
Post-splenectomy blood smear demonstrating Howell-Jolly bodies and target cells.

#Clinical #Pathology #BloodSmear #HowellJollyBodies #TargetCells #Splenectomy #Asplenic
#Clinical #Pathology ... HowellJollyBodies #TargetCells
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action of Bile ... Sequestrants Bile ... Sequestrants → ↓ Hepatic Bile ... Pool → ↑ Hepatic Bile ... Plasma LDL-C #biliary
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
genes coding for bile ... Dysfunction - Biliary ... certain drugs, biliary ... , carcinoma of biliary ... external pressure on bile
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
disease US — Normal Bile ... US - Dilated Bile ... Ducts • Common Bile ... Duct Stone • Biliary
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... gradual loss of bile ... inflammation and biliary ... #PBC #Primary #Biliary
Pulmonary Tuberculosis - Patterns of Involvement
 • Scarring, Nodules and Consolidation
    - Lobar
thickening • Miliary ... nodules representing miliary ... Cavitation, Abscess and Hilary ... #chest #xray #clinical
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
#Clinical #Path ... Smear #Codocytes #TargetCells
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... small intralobular bile ... of intralobular bile ... No extrahepatic biliary ... malignancy #Primary #Biliary
Illustrative examples of culture-confirmed erythema migrans. A, A single erythema migrans lesion of 8.5 × 5.0
punctum (presumed site ... preceding tick bite ... #Clinical #Dermatology
Indications for ERCP
1. Biliary Tract Diseases:
 • Biliary obstruction: Choledocholithiasis, Malignant biliary strictures, Benign biliary strictures
Biliary Tract Diseases ... : • Biliary obstruction ... Choledocholithiasis, Malignant biliary ... strictures, Benign biliary ... Oddi manometry • Bile