310 results
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 
1. Old samples
Dacrocytes, #Teardrops #TargetCells ... Echinocytes #BurrCells #Bite ... #Keratocyte #Blister
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Synthesis: in hepatocyte ... membrane (NOT within bile ... stimulated by bile ... accumulation in hepatocyte ... bilirubin into bile
Post-splenectomy blood smear demonstrating Howell-Jolly bodies and target cells.

#Clinical #Pathology #BloodSmear #HowellJollyBodies #TargetCells #Splenectomy #Asplenic
HowellJollyBodies #TargetCells
Localized skin infections and associations: Cellulitis, Bite wounds, Ulcers, Nodules, Eschars 

#SSTIs
#associations
#SkinInfections
#cellulitis
#ulcer
#eschar
#bites
#nodules
#differential
#diagnosis
#infectiousdisease
associations: Cellulitis, Bite ... ulcer #eschar #bites
Alpha-gal Syndrome (AGS) - Diagnosis Algorithm
Does patient have recurrent episodes of urticaria, angioedema or isolated GI
- Known tick bites ... irritation at site ... of tick bite
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
Illustrative examples of culture-confirmed erythema migrans. A, A single erythema migrans lesion of 8.5 × 5.0
punctum (presumed site ... preceding tick bite
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
Smear #Codocytes #TargetCells
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
genes coding for bile ... epithelial and hepatocyte ... external pressure on bile
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
14 days at the site ... of Ixodes bite