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table aflp differential hellp management pregnancy thrombocytopenia ttphus antibodies associations autoantibodies coagulation common cvid deficiencies deficiency disease diseases gap globulin
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
) • Advanced Liver ... Alcohol, Viral hepatitis ... Septic shock, Obstetric ... Summary #table #comparison ... #diagnosis #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... hepatitis Anti-CCP ... Dermatomyositis Anti-LKM (liver ... Associations #diseases #diagnosis ... #table #rheumatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
and Acute Fatty Liver ... Hemolysis, Elevated Liver ... #HELLP #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... EBV infection, Autoimmune ... the spleen or liver ... #oncology #diagnosis ... #differential #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... diseases and hepatitis ... : Pneumonia • Autoimmune ... thrombocytopenia and autoimmune ... hypogammaglobulinemia #immunology #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
vasculitis: 10%-16% Liver ... hepatitis, primary ... Nephrogenic DI Hematologic ... Symptomatic: artificial tears ... Sjogrens #Syndrome #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Sarcoidosis) • Liver ... Cirrhosis, ETOH, autoimmune ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... conjunctivitis, keratitis ... /EGPA • RA Diagnosis ... Polychondritis #rheumatology ... #diagnosis #management
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