12 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
process whereas secondary ... diseases • In secondary ... (PBC), or with systemic ... - Decreased tear ... #Diagnosis #Signs
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
- Differential Diagnosis ... Algorithm Idiopathic ... familial eosinophilia Secondary ... B-cell lymphomas), Systemic ... #Algorithm #allergy
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... Algorithm - Systemic ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #Diagnosis #Algorithm
Pediatric Vomiting - Gastrointestinal and Systemic Causes - Differential Diagnosis Algorithm
Hepatobiliary:
 • Acute Hepatitis
 • Acute
Gastrointestinal and Systemic ... - Differential Diagnosis ... Algorithm Hepatobiliary ... Poisoning • Food Allergy ... #Peds #Pediatrics
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... other diseases • Secondary ... Syndrome Diagnosis ... Nephrogenic DI Hematologic ... #Syndrome #Rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Type III Often Secondary ... Labs/Diagnosis: ... disorder (e.g. systemic ... Cryoglobulins #diagnosis
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
- Differential Diagnosis ... into a 4-pass system ... pass = Dangerous secondary ... cell activation syndrome ... #hematology #allergy
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Neurologic system ... enlargement - Sjögren's ... Inflammation of ear ... #differential #diagnosis ... #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
of 37°C to the near-freezing ... processes: • Systemic ... Cryofibrinogenemia Diagnosis ... Antiphospholipid syndrome ... hematology