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Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
patients with CKD ... since they are not able ... restricted due to hypercalcemia ... Purposes Only* #CKD ... #Nephrology #PhosphateBinders
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
calcium for K; also binds ... nonspecifically binds ... #medications #pharmacology ... #table #comparison ... #binders
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
used diuretics medications ... in CKD, Cirrhotic ... Spironolactone MCW Nephrology ... Pharmacokinetics #halflife #comparison ... #table
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #Management #Hyperkalemia ... #pharmacology #table ... #comparison #nephrology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... Improved outcomes in CKD ... #diabetes #medications ... #table #comparison
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Phosphate Binders ... and metal-free binder ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... edgarvlermamd - Nephrology ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology #Nephrology
Beta Blockers - Pharmacology Comparison Table
Metoprolol:
 • Receptors: β1
 • Indications: Rate control of a-fib/a-flutter, Suppression
- Pharmacology Comparison ... Table Metoprolol ... indicated in pt w/o CAD ... #Pharmacology #Comparison ... #Table #Receptors
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... : • CKD • Poorly ... Medications 2. ... potassium #high #nephrology