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Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework

Hypertension:
 • Hypertensive emergency
 • Hypertensive encephalopathy
• Cushing’s syndrome ... Pre-Eclampsia Renal ... Acute/Chronic renal ... failure • Renal ... • Scleroderma renal
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Algorithm Extra-renal ... loss (Diarrhea) Renal ... SAME, Cushing Syndrome ... , Gitelman syndrom ... Diagnosis #Algorithm #causes
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Malignant HTN • Renal ... thrombosis • Renal ... Sickle cell) • Renal ... Compression of left renal ... TURP/Biopsy Renal
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Differential Diagnosis Renal ... Familial: Bartter syndrome ... and Gitelman syndrome ... hypomagnesemia Renal ... Hypercalcemia, Post renal
Causes of Metabolic Alkalosis - Differential Diagnosis
Chloride depletion syndromes
 • Gastrointestinal losses
    -
Causes of Metabolic ... Chloride depletion syndromes ... villous adenomas • Renal ... administration Other causes ... Differential #Diagnosis #Causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... gastrointestinal K loss • Renal ... hypokalemia • Renal ... diagnosis #algorithm #causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... UNa > 20: • Renal ... Bicarbonaturia with renal ... Acute or chronic renal ... Diagnosis #Algorithm #Causes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
diarrhea / IBD Renal ... - Transient renal ... - Familial renal ... Mg wasting syndromes ... Classification #Causes
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... Defects Fanconi Syndrome ... tubule Bartter Syndrome ... Henle Gitelman Syndrome ... : Distal convoluted
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
: • Renal parenchymal ... disease - Renal ... of renal disease ... Renovascular disease - Renal ... Bilateral selective renal