23 results
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Primary Bone Tumors ... • Aneurysmal Bone ... Histiocytoma #Primary #Bone ... #Bony #Tumors # ... #Causes #Oncology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
demineralization) • Renal disease ... • Anemia 78% (bone ... macrocytic • Bone ... clonal cell in bone ... #Management #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
g/dl LLN B - Bony ... more: • Clonal bone ... Causes of false- ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Chronic Joint Pain - Differential Diagnosis Algorithm 
Intra-Articular
 - Bone
     • Stress
Intra-Articular - Bone ... Osgood-Schlatter Disease ... Ganglion Cyst - Bone ... #Algorithm #Orthopedics ... #Causes
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
3: Necrosis of bone ... destroying thin bony ... of the temporal bone ... inner cortical bone ... #otology
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
- Differential Diagnosis ... Tumours - See Bone ... • Bone Marrow ... #Algorithm #Orthopedics ... #Causes
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... BrighamChiefs #Bone ... #differential #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... old, ~10,000 new cases ... diagnosed annually ... • Bone marrow ... treatment #hematology #oncology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... swelling of the bone ... Rule out other causes ... as the collar bone ... osteoarticular and skin disease
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Peripheral Vascular Disease ... fractured long bone ... • Dislocated Bone ... #Algorithm #Orthopedics ... #Causes