6 results
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... chemosensitive malignancy ... Walid Malki, MD, MS ... #Syndrome #TLS ... #oncology #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: • Pathophysiology ... organ damage • Treatment ... Syndrome: • Pathophysiology ... #diagnosis #management ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... APML #diagnosis #management ... #hematology #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... TLS (tumor-lysis ... syndrome): - Hematologic ... Hypercalcemia of malignancy ... → no immediate treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... and Arthritis Malignancy ... Adenocarcinoma Treatment ... Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... Pathophysiology ... trigger: Infections, malignancy ... #Hematology #HemeOnc