26 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
predispose to other orthopedic ... common sites: hip ... , shoulder ... diagnosis #causes #hematology
Causes of Erythema Nodosum - Mnemonic

NO cause found in 60% of cases
Drugs (antibiotics e.g., sulfonamides, amoxicillin)
Oral
Sarcoidosis or Lofgren's syndrome ... Viral: HSV, EBV, HIV ... Differential #Diagnosis #Dermatology
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
EBV, CMV), Acute HIV ... diseases, Toxic shock syndrome ... , DRESS, Sweet syndrome ... Differential #Diagnosis #dermatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Ig A vasculitis/HSP ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Quinidine • HIT ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Vasculitis: - Ig A (HSP ... Disease • Cogan syndrome ... Vasculitis #skin #dermatology ... #rheumatology #
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
etc) - Viral: HIV ... antiphospholipid syndrome ... Diagnosis #Framework #hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
- NEJM 2011 - Hip ... Transfusions should ... Transfusion #Thresholds #Hematology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
aspergillosis) - Viral (HIV ... Hypereosinophilic Syndrome ... Diagnosis #Causes #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... - HCV - HIV ... immunodeficiency virus (HIV ... Anemia #oncology #hematology