34 results
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... Erythematosus #SLE ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... with Systemic Lupus ... Erythematosus (SLE ... should have other symptoms ... #Differential #Diagnosis
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
(SLE) - Typical ... Signs/Symptoms ... , Arthralgia / arthritis ... #Signs #Symptoms ... #diagnosis #rheumatology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... fingers, radial wrist ... Extra-articular signs ... pathophysiology #signs ... #symptoms #diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... lesions • Discoid lupus ... #dermatology #joint ... #differential #diagnosis ... #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #rheumatology # ... #differential #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... - Arthralgia, Arthritis ... pathophysiology #signs ... #symptoms #diagnosis
Arthritis of the Hand - Arthritis Patterns

Osteoarthritis:
• Osteoarthritis of the hand usually involves the DIP and
ulnar deviation • SLE ... • MCP + PIP + Wrist ... Hemochromatosis • Wrist ... patterns #hand #diagnosis ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
: - Arthritis ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology