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diagnosis erythematosus hematology sle treatment systemic activation calcium clues cppd deposition differential disease fungal gout hemophagocytic hlh infections infectiousdiseases lymphohistiocytosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebritis: Labs ... Erythematosus #SLE #CNS ... #neurology #rheumatology ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... nervous system (CNS ... SJIA], systemic lupus ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... especially in the wrists ... pericarditis » is...lupus ... when infection has ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... erythematosus (NPSLE): • May ... involve PNS and ... CNS • Headache ... Erythematosus #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
myopathy • Anti MAG ... Scleromyxedema (CNS ... +GI+CVS+joints) ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Diagnosis and Management ... knees, fingers, wrist ... • Arthritis may ... Gout #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
(depending on CNS ... underlying condition may ... HLH #Treatment #management ... #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
joints (shoulders, wrists ... often involves the wrists ... atypical locations: Wrist ... Deposition #Disease #Rheumatology ... #diagnosis #management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
TAFRO syndrome was ... including systemic lupus ... histopathologic changes in LNs ... TAFRO #diagnosis #management ... #rheumatology #
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... antigen assay has ... especially the CNS ... MC: CNS CSF: • ... Fungal #Diagnosis #Management
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