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differential lfts causes gastroenterology hematology transaminitis acute dili function hepatitis syndrome tests treatment abnormal acidosis aclf acromegaly activation anemia bacterial
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Liver Injury (DILI ... #algorithm #gastroenterology ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... 1000): • DILI (Drug-induced ... liver injury) ... #hepatology #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
: Liver Injury ... → liver test abnormalities ... valproate, azoles), Drugs ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Stepwise Diagnosis ... Algorithm DILI ... #Injury #Diagnosis ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... , Recreational Drugs ... #Acute #algorithm ... #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... Blood Smear • Drugs ... Function Tests ... #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... extrahepatic source - Tests ... #algorithm #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... hepatocellular injury ... impaired uptake (drugs ... Interpretation #diagnosis ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... 15X ULN - Drugs ... #diagnosis #hepatology
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