22 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Autoimmune (AIHA)"Cold ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... anemiaCold ... younger pts) Differential ... test #cold # ... #hematology #diagnosis
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Cell Agglutinate: Cold ... , Paroxysmal cold ... RBC #Morphology #differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Increased Requirement (e.g ... Liver Function Tests ... #Causes #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Autoimmune: Warm AIHA, Cold ... Defects: Sickle cell anemia ... Laboratory Tests ... #Diagnosis #hematology
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
Pathophysiology and Differential ... Diagnosis Obesity ... Disease - Especially COPD ... Metabolism Severe Anemia ... #Diagnosis #cardiology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... reference range (or 2-fold ... Direct Coombs’ test ... #Diagnosis #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... practices that could ... K), H. pylori test ... , ANA (e.g., SLE ... changes), high MCV anemia
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... (to support a diagnosis ... ANA and RF (if clinical ... #testing #Rheumatology
Chronic Diarrhea - Workup
Osmotic:
 • Consider food diary and trial avoiding certain foods or meds, Consider
gap > 125mOsm/kg ... hydrogen breath test ... show melanosis coli ... Abdominal imaging (CT, ultrasound ... #differential #