28 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... Associated with skin ... • Specific for SLE ... severe disease Treatment ... Summary #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... • Immunologic Workup ... life-threatening • Treatment ... Management #Summary #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
LcSSc) - distal skin ... distal to elbows/wrists ... changes): skin ... Scleroderma #SSc #rheumatology ... symptoms #testing #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... erythematosus (SLE ... 30% and 60% of SLE ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... glucocorticoid treatment ... symptoms (eg, skin ... Differential #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... K), H. pylori test ... thyroid function test ... , ANA (e.g., SLE ... #hematology
WHAT test - Wrist Hyperflexion and Abduction of the Thumb 

The wrist is hyperflexed and the
WHAT test - Wrist ... Thumb The wrist ... Abduction #Thumb #Test ... Tenosynovitis #PhysicalExam ... #orthopedics #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... constitutional symptoms • Treatment ... • Immunologic Workup ... life-threatening • Treatment ... comparison #table #rheumatology
Eichhoff's Test in de Quervain's Tenosynovitis

1) Patient makes a fist with fingers wrapped around the thumb
2)
Eichhoff's Test ... ulnar deviates the wrist ... clinical #video #physicalexam ... #orthopedics #rheumatology ... #wrist
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
(this is a skin ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment ... signs #symptoms #rheumatology