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Hemolytic Anemia - Hemolysis Diagnostic Workup

Infographic by: Howard Ong

#Hemolysis #Hemolytic #Anemia #Algorithm #MAHA #TTP #Diagnosis #Workup
Hemolytic Anemia ... - Hemolysis Diagnostic ... #Hemolytic #Anemia ... #TTP #Diagnosis ... #Workup #Hematology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... #Hemolytic #Anemia ... #Causes #Workup ... #Hematology #Diagnosis ... GrepMed Recommended Text
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... TTP/HUS indicates ... thrombocytopenia, Hematology ... 2012, p 193 #Diagnosis ... Thrombocytopenia #Evaluation
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Gastrointestinal Evaluation ... , diagnose iron ... • Additional laboratory ... Test for celiac ... #workup #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Evaluation for ... value is low, tests ... anemia Indirect ... #Workup #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... thrombocytopenia - DIC, TTP ... #Diagnosis #Algorithm ... #workup #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Fragmentation - MAHA: TTP ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... Vasculitides, IBD, Celiac ... #Algorithm #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... - Bone marrow evaluation ... Refractory ITP,
Celiac Disease - Diagnosis Algorithm
IgA TTG has high sensitivity and specificity of ~ 98% and is
Diagnosis Algorithm ... IgA TTG has high ... serologic marker for evaluating ... -A positive test ... #workup