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rheumatology differential druginduced physicalexam sle syndrome treatment activation algorithm alopecia asboehansen blister clinical coagulation comparison dic dil disseminated erythematosus hair
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... versus DIL • Laboratory ... • Immunologic Workup ... Positive in 60-80% of cases ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... #diagnosis #management
Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign") Asboe-Hansen sign is the extension
Best-detected by ... clinical tool for diagnosing ... evaluation of TEN ... #PhysicalExam #Video ... #Blister #Dermatology
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 Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
- Differential Diagnosis ... Disease: Discoid lupus ... Scarring Alopecia: Lupus ... Tests: • TSH ... #dermatology #Hairloss
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity is the diagnostic ... value is low, tests ... indirect antiglobulin tests ... #Workup #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Autoimmune Vasculitis (lupus ... deficiency Work ... Fecal occult blood test ... #dermatology #physicalexam
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Hemorrhagic bullae ... venipuncture sites Laboratory ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... other etiology • Laboratory ... blockers had the best ... #diagnosis #management ... #Dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
calcium-b) • Laboratory ... • Immunologic Workup ... Discontinuation of causal ... #diagnosis #treatment ... #management
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