87 results
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
B12 and Folate Deficiency ... • B12 Deficiency ... Thomas DeLoughery ... #MMA #folate #deficiency ... VitaminB12 #diagnosis #hematology
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Lupusreference #TMAs ... Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... blood loss (Fe deficiency ... Non-infectious (malignancy, rheumatologic ... Thrombocytosis #Differential ... causes #Platelets #hematology
Gout Management in CKD
 • Colchicine
 • NSAID
 • Glucocorticoid
 • ACTH
 • Interleukin-1 Inhibitors

#Gout #Management
Management #CKD #rheumatology ... #treatment #comparison
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Acute hemolysis, deficiency ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Thrombocytosis #Platelets #Differential
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate Deficiency ... develop folate deficiency ... Thomas DeLoughery ... #FolicAcid #differential ... #diagnosis #hematology
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
Thomas DeLoughery ... TEG #Management #treatment ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... effect following treatment ... malignancy • Iron deficiency ... Thrombocytosis #Differential ... Algorithm #Causes #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... severe, ADAMTS13 deficiency ... HUS) Treatment ... #rheumatology # ... hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison ... Diagnosis #Table #Hematology