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diagnosis differential rheumatology erythematosus lupus systemic algorithm management signs symptoms anemia autoantibodies babesia babesiosis causes chronic clinical dermatology fuo hematology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
Causes of Fever ... Autoimmune: • SLE ... Other: • Drug fever ... • Factitious fever ... Protozoa (eg. malaria
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
B19 infection Malar ... rash • SLE ... • Rheumatic fever ... IBD • RA • SLE ... erythematosus • SLE
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Complement Levels: SLE ... other hemorrhagic fevers ... Legionellosis, Malaria
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... rash 40% - Fever ... involvement 3% SLE-Related ... Lupusreference #SLE
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
genotypes): SS, SC, SE ... suspected, consider malaria ... bartonella (oroya fever
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Leishmaniosis, malaria ... Autoimmune diseases: SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... Photosensitivity • Malar ... to: Arthritis, Fever ... : Drug induced SLE
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Erythematosus (SLE ... Symptoms Alopecia, Fever ... , Malar rash, Photosensitivity ... Erythematosus #SLE
Strongyloides Stercoralis EPIDEMIOLOGY - ASSOCIATED WITH SOUTHEASTERN U.S.: • 0-6% US Prevalence of those: • ~30% Asymptomatic
and distension, fever ... management #parasites #Threadworm ... #lifecycle
Babesiosis on Peripheral Smear 85 M from SE USA, hx splenectomy, IgG4 plasmacytic syndrome: F, chills, profound
Smear 85 M from SE ... Splenectomized pt with fever ... babesia microti, malaria ... invasion & lysis: fever
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