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diagnosis differential workup management causes leukemia algorithm aplastic cbc chronic cll criteria disease hemeonc hemophagocytic hepatology hlh infectiousdiseases laboratory lymphocytic
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Definition • Pathophysiology ... #Aplastic #Anemia ... #diagnosis #oncology ... #hematololgy
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Non malignant hematologic ... following EtOH induced thrombocytopenia ... states • Non-hematologic ... Iron deficiency anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... smear, HIV/HCV testing ... changes), high MCV anemia ... or if a primary hematologic ... Causes #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... or thrombocytopenia ... or thrombocytopenia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Schistocytes, thrombocytopenia ... ARUPLabs #Hemolytic #Anemia ... Algorithm #workup #hematology ... #testing
Diagnosing Brucellosis Epidemiological Exposures - Endemic Regions - Clinical Micro Lab Technicians - Animal/Vaccine Exposure: Vets, Slaughterhouse workers, hunters - Unpasteurized
Diagnostic Tests: - CBC ... + Chemistry: Anemia ... /Leukocytosis, Thrombocytopenia ... Criteria #Workup #Testing
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
fibrin-split products - Thrombocytopenia ... deficiency - Anemia ... leads to chronic anemia ... LiverFailure #Hepatic #Hepatology ... Laboratory #Diagnosis #Testing
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
: ↑↑ ferritin, Anemia ... , Thrombocytopenia ... consistent with HLH OR Meeting ... Lymphohistiocytosis #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Immune Aplastic Anemia ... infections/fevers • Thrombocytopenia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Neutropenia, anemia ... , thrombocytopenia ... diagnosis #workup #oncology ... #hematology
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