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diagnosis hematology management leukemia causes classification hodgkins lymphocytic lymphoma myelodysplastic photo syndrome algorithm basophilia basophils blastomycosis cancer common comparison cutaneous
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... weeks without infection ... diagnosis #workup #oncology ... #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... which are released during ... Disorders: • Chronic ... Diabetes/DKA Infections ... : • helminth infections
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... #oncology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
synchronous or appearing during ... Infectious manifestations ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... history of recurrent infections ... disease • Infectious ... community-acquired infections ... infections (Epstein-Barr
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... Autoimmune diseases • Clinical ... Etiology: - Infections ... NonHodgkins #comparison #oncology ... #hematology
Ulcerative Blastomycosis Skin Lesion 57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
heaped up borders); differential ... : basal cell ca, ... squamous cell ca ... Indiana University Infectious ... #clinical #photo
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... diseases - HIV infection ... Chronic thromboembolic ... Langerhans cell ... Classification #Diagnosis #Differential
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... immunophenotype Clinical ... Complications: 1) Infection ... #Leukemia #oncology ... #hematology #hemeonc
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