12 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... Infectious manifestations ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... violaceous, nontender cutaneous ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... weeks without infection ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
e.g., HIV), EBV infection ... Etiology: - Infections ... disease: GI, neuro, cutaneous ... NonHodgkins #comparison #oncology ... #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... history of recurrent infections ... disease • Infectious ... community-acquired infections ... infections (Epstein-Barr
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... - Due to Viral infection ... Polyclonal - Viral Infection ... Check For: • Infections ... Polyclonal IgM post infectious
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Most common extra cutaneous ... Upper respiratory infection ... gastrointestinal infection ... #diagnosis #dermatology ... #oncology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacteria (NTM) Infections ... Factors For NTM Infections ... • Disseminated infections ... lung infections ... surgical site infections
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Marrow Failure • Chronic ... • Parvovirus infection ... blood count with differential ... #oncology