31 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... recessive salt-losing ... #Syndrome #Pathophysiology
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Defects Fanconi Syndrome ... loop of Henle Gitelman ... Syndrome: Distal ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... syndrome from Bartter ... syndrome • Urine ... Chloride • Urine Ca ... krithicism #Gitelman
Alteplase (t-PA) for Acute Ischemic Stroke: 
Dosage, Mixing, and Administration Instructions

#TPA #Thrombolytics #Stroke #CVA #Dosage #Dosing
Instructions #TPA #Thrombolytics ... #Stroke #CVA #Dosage ... #Dosing #Mixing
tPA Code Stroke Dosing Chart

Total Dose = 0.9 mg/kg (maximum dose =90 mg)
 - give 10%
tPA Code Stroke Dosing ... 1 hour #TPA #Dosing ... #Dose #CVA #Thrombolytics
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Phosphorus -> Ca-Phos ... #TumorLysis #Syndrome ... #TLS #Pathophysiology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... hypokalemic salt-losing ... cotransporter • Gitelman's ... Pseudo Bartter-Gitelman ... nephrology #management #pathophysiology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... • Increased CVP ... #cardiorenal #syndrome ... #Mechanisms #pathophysiology
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Irritable Bowel Syndrome ... (IBS) - Pathophysiology ... functional somatic syndromes ... depression, Poor coping ... #Pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
- Budd Chiari Syndrome ... - Protein-Losing ... Complications #pathophysiology