13 results
Alteplase (t-PA) for Acute Ischemic Stroke: 
Dosage, Mixing, and Administration Instructions

#TPA #Thrombolytics #Stroke #CVA #Dosage #Dosing
Instructions #TPA #Thrombolytics ... #Stroke #CVA #Dosage ... #Dosing #Mixing ... #Instructions #Pharmacology
tPA Code Stroke Dosing Chart

Total Dose = 0.9 mg/kg (maximum dose =90 mg)
 - give 10%
tPA Code Stroke Dosing ... 1 hour #TPA #Dosing ... #Dose #CVA #Thrombolytics ... #Stroke #Pharmacology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... recessive salt-losing ... Contraction → ↑ Renin ↑ Ca ... #Pathophysiology ... #nephrology #diagnosis
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... • Increased CVP ... #cardiorenal #syndrome ... #Mechanisms #pathophysiology ... #nephrology
Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy

• No previous history of
Antiphospholipid Syndrome ... Previous history thrombotic ... Antiphospholipid #Syndrome ... Aspirin #LWMH #Dosing ... #Pharmacology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... prevention (statin for CVA ... Erythematosus #SLE #CNS #neurology
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors
Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
P2Y12 inhibitors during ... acute coronary syndrome ... inhibition and risk of thrombotic ... ticagrelor #prasugrel #pharmacology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Transient K+ efflux moving ... leading to slow Ca ... Antiarrhythmics #Pharmacology ... Classification #Classes #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... Etiology: • Pathophysiology ... narrowing on MRA/CTA ... diagnosis #management #neurology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
acetaminophen dosing ... D-lactate (short bowel syndrome ... sedation, narcotics, CVA ... Diagnosis #Summary #Nephrology