11 results
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Pharmacology of ... #Pharmacology # ... Comparison #Table ... Loop #Thiazide #CHF ... #Cardiology #Management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... • Nephrogenic diabetes ... Lithium-induced nephrogenic diabetes ... DDAVP) • Central diabetes ... #Nephrology #Pharmacology
Characteristics of Common Lipid Disorders
Polygenic hypercholesterolemia
Atherogenic dyslipidemia
 • Frequently accompanied by central obesity or diabetes
Familial hypercholesterolemia,
central obesity or diabetes ... Family history, CHD ... lipid #disorders #diseases ... #comparison #table ... defects #diagnosis #differential
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Correction of diabetic ... Tubulointerstitial renal disease ... Drugs: - Loop diuretics ... Causes #diagnosis #differential ... medications #drugs #pharmacology
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Failure, Valvular Disease ... Arrhythmias / CHB ... vasoactive drug pharmacology ... inopressors #diagnosis #management ... #comparison #table
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • K sparing diuretics ... (Uncontrolled diabetes ... • Addison’s disease ... Food - Avoid in CRF
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
coronary artery disease ... endomyocardial biopsy Pharmacology ... Dinitrate • Diuretics ... heartfailure #diagnosis #management ... #cardiology #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • K sparing diuretics ... (Uncontrolled diabetes ... • Addison’s disease ... Food - Avoid in CRF
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
The differential ... Dehydration: neurologic disease ... unavailable 2) Osmotic Diuresis ... post-obstructive 3) Diabetes ... Diagnosis #Treatment #management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
excreted using diuretics ... #diagnosis #differential ... #algorithm #management ... #heartfailure #chf ... icu #clinical #pharmacology