15 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... death Neutropenic Fever ... New-onset back pain ... Dyspnea, chest pain
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... is the main clinical ... ALT ↑ bilirubin level ... #Diagnosis #Management ... #Hematology #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
malaise) - Muscle pain ... Inflammation and pain ... , breast CA - Hematologic ... #diagnosis #dermatology ... #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... effusions, weight gain ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... index < 2 • EPO Level ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
B for initial management ... - Virtually never ... infections) - Main ... adverse effects = Hematologic ... #Pharmacology #Antibiotics
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... following: • Fever ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, fever, joint pain ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
tool to assess level ... Propofol infusion syndrome ... No pharmacologic ... (Haldol) - No pharmacologic ... CriticalCare #diagnosis #management
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline

First Line Treatment for HCC with Preserved
with Preserved Liver ... Systemic #Treatment #Management ... #Hepatology #Gastroenterology ... #oncology #Pharmacology