11 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
is the main clinical ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... • Bicytopenia Treatment ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... symptoms: - Muscle pain ... Muscle swelling - Fever ... - Abdominal pain ... per day until stable
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... irrigation • Management ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... effusions, weight gain ... APML #diagnosis #management ... #hematology #oncology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... swelling, significant pain ... Gout #diagnosis #management ... #treatment #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
vasculitis: 10%-16% Liver ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... #Rheumatology # ... Diagnosis #Management
Alcohol Use Disorder - Maintenance Treatment
Naltrexone (first line) - First line for most people without contraindications
- Maintenance Treatment ... if also chronic pain ... if neuropathic pain ... #management #pharmacology ... #table #addiction
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
effects in the treatment ... dyspnea, chest/back pain ... #valleyfever #management ... #comparison #table ... #pharmacology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Sudden onset of pain ... Nonspecific symptoms: Fever ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management